Alpha-Lipoic Acid Supplements: Benefits, Dosage and Safety
Alpha-lipoic acid supplements are an antioxidant used for diabetic nerve pain. A meta-analysis found it may improve neuropathy symptoms, with intravenous forms studied more than oral. It may lower blood sugar, so people on diabetes medicines should monitor levels.
Evidence at a glance
| Use | Grade | What the research shows |
|---|---|---|
| Diabetic neuropathy symptoms | C | Some improvement in symptoms in a meta-analysis. |
A: strong, consistent human evidence · B: moderate · C: limited or mixed · D: good evidence of no benefit.
Alpha-lipoic acid is made in small amounts by the body and helps convert food into energy.
How to take it
Studies commonly used 600 mg daily. See supplements for nerve pain.
Safety and interactions
Can cause nausea. Monitor blood sugar if you take diabetes medicines.
Always tell your doctor and pharmacist about the supplements you take. Check combinations with our interaction checker.
Sources
This page is for education and is not a substitute for advice from your doctor. Read our medical disclaimer.