NAC (N-Acetylcysteine) Supplements: Benefits, Dosage and Safety
NAC supplements thin mucus and boost glutathione, the body's main antioxidant. A meta-analysis suggested NAC may reduce flare-ups in chronic bronchitis and COPD. In hospitals, NAC is the antidote for acetaminophen overdose.
Evidence at a glance
| Use | Grade | What the research shows |
|---|---|---|
| Fewer COPD/chronic bronchitis exacerbations | C | A meta-analysis suggests fewer flare-ups. |
A: strong, consistent human evidence · B: moderate · C: limited or mixed · D: good evidence of no benefit.
N-acetylcysteine is made from the amino acid cysteine.
How to take it
Studies used 600–1,200 mg daily. Talk to your doctor if you have a lung condition. See lung health supplements.
Safety and interactions
Can cause nausea and digestive upset. People with asthma should use caution.
Always tell your doctor and pharmacist about the supplements you take. Check combinations with our interaction checker.
Sources
This page is for education and is not a substitute for advice from your doctor. Read our medical disclaimer.