Best Supplements for Skin Health: Collagen, Omega-3s and Zinc

Collagen peptides modestly improved skin hydration and elasticity in trials; zinc has some evidence for acne. Sunscreen beats any pill. See doses and limits.

By the editorial team · Updated Oct 14, 2026 · 3 sources cited

The short answer

The best supplements for skin health offer modest benefits. Collagen peptides improved skin hydration and elasticity in a meta-analysis of trials, many industry-funded. Zinc has some evidence for acne, and omega-3s may help some inflammatory skin conditions. Daily sunscreen, not smoking and proven skincare do far more for skin aging.

Evidence-ranked options

SupplementEvidenceTypical doseNotes
Collagen peptidesC2.5–10 g a day for 8–12 weeksModest hydration and elasticity improvements.
Zinc (acne)CAs studied; under 40 mg/day long termLess effective than standard acne treatments.
Omega-3C1–2 g a daySome evidence in inflammatory skin conditions.
Vitamin C (if intake is low)CMeet the RDANeeded for collagen; topical forms are studied separately.

A: strong · B: moderate · C: limited or mixed · D: good evidence of no benefit. See the evidence database.

Skin basics

Broad-spectrum SPF 30+ every day, moisturizer, not smoking and enough sleep. Related: hair and nails.

Ingredient guides

Frequently asked questions

What's the best anti-aging supplement for skin?

None outperform daily broad-spectrum sunscreen and avoiding smoking. Collagen has the most supplement research.

Can supplements cure acne?

No. Proven treatments include topical retinoids, benzoyl peroxide and prescription options.

Sources

  1. de Miranda RB et al. Effects of hydrolyzed collagen supplementation on skin aging: systematic review and meta-analysis. Int J Dermatol. 2021
  2. MedlinePlus: Aging Skin
  3. MedlinePlus: Acne

Educational content, not medical advice. Read our medical disclaimer.

Other health goals